New guidelines from the American Academy of Neurology (AAN) recommend that clinicians consider using plasma exchange (also known as plasmapheresis, a blood-cleansing procedure) for a number of conditions for which it has shown benefit. In MS, the guidelines suggest it may be effective as a secondary therapy for exacerbations unresponsive to corticosteroids in people with relapsing forms of MS, and may be useful for severe, rapidly progressive MS and similar disorders (acute fulminant demyelinating CNS disease).
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