As it is a gradual transition, there isn’t one single test or exam that can diagnose SPMS—clinical, imaging, immunologic, and pathologic criteria have yet to clearly establish when RRMS transitions to SPMS. Still, there are risk factors that may affect your patients’ transition from RRMS to SPMS.1,2
All patients experience unique changes to their disease, and tracking their transition early on can potentially lead to an improved prognosis over time. Start evaluating MS progression by reviewing their history.3
Here are some of the clues that may inform a diagnosis.1,4-8
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