Novel Coronavirus Disease 2019 (COVID-19) and Neurodegenerative Disorders

During the last few months, the whole humanity is experiencing largest and most severe sudden influx of COVID-19 outbreak caused by the novel Coronavirus (CoV) originated from Wuhan, China. According to the WHO reports, total 3862676 positive cases and 265961 deaths have been recorded worldwide due to COVID-19 infection as of 09 May 2020. CoVs are a large family of viruses (enveloped, single-stranded RNA viruses), which includes Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome-related Coronavirus (MERS-CoV). New SARS CoV2 is the members of Betacoronavirus genus. These viruses cause infections in bats, camels and humans, and a few other associated species. Despite many neurologic complications associated with SARSCoV-2 infection, it is still unclear whether these symptoms results from direct neural injury or due to some other reason. Currently, it appears that most of the neurological symptoms of COVID-19 are non-specific and secondary to the systemic illness. A single case of acute hemorrhagic necrotizing encephalopathy has been reported. SARS-CoV-2 associated Guillain-Barré syndrome is an atypical case. Till today, no convincing evidence is available to confirm that the SARS-CoV-2 virus directly affects nerves system in humans. However, post-infection surveillance will be necessary to identify the possible post-COVID-19 neurologic syndromes. This article is protected by copyright. All rights reserved.

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