What people with MS and care partners need to know about advancements in monitoring MS activity

Biomarkers are measurable tests such as blood tests, spinal fluid tests and MRI that can help your neurologist diagnose and manage your multiple sclerosis. Biomarkers provide objective data that can help clinicians identify MS earlier, track progression, and help determine response to treatment.  As we know, MRI and spinal fluid analysis have been used for many years to aide in early and accurate diagnosis. In addition, MRI is used frequently to track response to MS disease modifying therapies.  

New serum biomarkers – meaning those identified in the blood can be measured and help with ongoing disease monitoring. One biomarker that has been identified in the blood is called neurofilament light chain or NfL. NfL is a protein that helps to provide support to nerves in the brain and spinal cord.  When measured in the blood it is known as serum NfL or sNfL. The amount of sNfL in the blood goes up when there is damage to the nerves in your central nervous system. This information can be helpful in understanding your disease activity.

The use of current biomarkers, and the future addition of new biomarkers will help aide in earlier and more accurate diagnosis and help you and your neurology provider develop a treatment plan that is more personalized to your needs.

Please see the graphic below for more information about sNfL, including questions that you can ask your neurology provider the next time you have a visit. —
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Article Source: MS Coalition

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