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Int J MS Care; ePub 2017 May 18; Marrie, et al
June 6, 2017
Depression and, to a greater extent, anxiety remain underdiagnosed and undertreated in multiple sclerosis (MS), according to a recent study, and both substantially contribute to reduced health-related quality of life (HRQOL) in MS. Researchers linked clinical and administrative data for 859 participants with MS; HRQOL was measured by the Health Utilities Index (Mark III). They classified participants as depressed or anxious using administrative data, self-reported physician diagnoses, and the Hospital Anxiety and Depression Scale (HADS). They found:
- Lifetime prevalence estimates for depression were approximately 30% regardless of methods used, but 35.8% with current depressive symptoms were not captured by either method.
- Prevalence estimates of anxiety ranged from 11% to 19%, but 65.6% with current anxiety were not captured by either method.
- Prior diagnoses did not decrease HRQOL after accounting for current symptoms.
Citation:
Marrie RA, Patten SB, Berrigan LI, et al. Diagnoses of depression and anxiety versus current symptoms and quality of life in multiple sclerosis. [Published online ahead of print May 18, 2017]. Int J MS Care. doi:10.7224/1537-2073.2016-110.
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