Examples
| Generic Name | Brand Name |
|---|---|
| dexamethasone | |
| methylprednisolone | Depo-Medrol, Solu-Medrol |
| prednisone |
How It Works
Methylprednisolone, prednisone, and dexamethasone are corticosteroids. These medicines shorten multiple sclerosis (MS) attacks by reducing inflammation on the brain and spinal cord.
A high dosage of methylprednisolone may be given through a vein (intravenous, or IV) daily for 3 to 5 days during an MS attack. Prednisone or methylprednisolone may then be given by mouth for several days after the IV treatment.
Why It Is Used
Corticosteroids may be used to treat sudden, severe (acute) MS attacks and acuteoptic neuritis.
How Well It Works
Treatment with corticosteroids may reduce the symptoms of MS attacks and help you recover more quickly.1 There is no convincing evidence that corticosteroids can reduce the progression of MS.
Side Effects
Corticosteroids cause few side effects when used over a short period of time. People with MS who use a short course of corticosteroids to treat severe symptom attacks may have:
- Sleep problems.
- Anxiety and agitation.
- Depression.
These problems will usually go away after you stop taking the medicine.
When corticosteroids are used in high doses or for longer periods of time, they can have more serious side effects, including:
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