The Design of MRI-Related Clinical Trials in MS

Stuart SchlossmanMRI

Developed by Khawai.

Understanding and analyzing the design of past clinical trials is a key factor in planning future trials.

This visualization details the design of 88 clinical trials with magnetic resonance imaging (MRI) reports published between 1993 and 2014. It makes it easy to see which of five key measurements were reported in each trial and when during the course of that trial those measurements were made.

The measurements are:

  • Brain Volume
  • T2-hyperintense lesion volume (Volume T2)
  • Combined Active Lesion (CAL)
  • Gadolinium-enhancing lesion (GdEnh Lesion)
  • Expanded Disability Status Scale (EDSS)

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