A large UK study finds that tetrahydrocannabinol (THC) from marijuana doesn’t slow multiple sclerosis progression.
BY NSIKAN AKPAN, PHD | JUL 23, 2013
A large clinical trial from the UK has found tetrahydrocannabinol (THC), an active ingredient of marijuana, doesn’t prevent the progression of multiple sclerosis (MS). The study was published today in Lancet Neuology, while the findings were first announced at a medical conference last year.
The findings comes from the CUPID (Cannabinoid Use in Progressive Inflammatory Brain Disease) study, an investigation from the University of Plymouth that involved from the 500 patients with progressive MS, a subtype of MS characterized by a progressive worsening of the condition. Plymouth’s study is the largest to date on the use of the cannabinoid THC with MS.
Multiple sclerosis, an autoimmune disease that is the most common cause of neurological disability in young adults, typically begins in one of two ways. Those with relapsing-remitting MS — 80 percent of initial cases — experience intermittent attacks of severe symptoms, which can include impaired vision, severe fatigue, muscle spasms, or balance disruption.
A second possible diagnosis during the early stages is primary-progressive MS, which features these symptoms from the outset and is marked by the gradual worsening of the disease.
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