What may work better than existing drugs to treat severe multiple sclerosis? Stem cells.
A phase 2 clinical study from an international group of research centers compared head-to-head autologous hematopoietic stem cell transplantation (AHSCT) and mitoxantrone in treating patients with secondary progressive or relapsing-remitting multiple sclerosis. The findings showed that MRI-detected brain lesions were reduced by 79% in patients undergoing AHSCT compared to patients treated with mitoxantrone.
“Intense immunosuppression followed by AHSCT is significantly superior to mitoxantrone in reducing MRI activity in severe cases of multiple sclerosis,” wrote the authors. “These results strongly support further phase 3 studies with primary clinical endpoints.” Results appeared in “Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis,” published in the journal Neurology. continue reading
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
MS Views and News helps to provide information for all affected by MS
Keep up to date with the news and information we provide
by signing up by clicking here
.=======================================================
Visit our MS Learning Channel on YouTube: http://www.youtube.com/msviewsandnews