Symptoms & Diagnosis of SPMS
SPMS symptoms are not necessarily different from the symptoms that govern Multiple Sclerosis overall; the defining feature of the disease type is its shift in pattern. However, symptoms associated with Secondary Progressive MS include an increase in weakness and lack of coordination; stiff, tight leg muscles; loss of bowel and bladder control; and increased fatigue, depression, and problems thinking than before — all of which do not appear to come and go.
As noted above, SPMS diagnosis is predicated on steady communication between patient and doctor, since the diagnosis is not made via a diagnosis assay, but rather through professional observation and tracking of the disease. While the diagnosis may seem subjective, updating a diagnosis from Relapsing-Remitting to Secondary Progressive is very important, since the approach to treatment may change as well. In order to get the most informed diagnosis for Secondary Progressive MS, doctors use the Kurtzke disability scale to aid the measurement of the disease progression.
Causes of Secondary Progressive MS
One of the key areas of research for MS is an understanding of why Relapse-Remitting Multiple Sclerosis eventually progresses into Secondary Progressive MS in so many cases, as the cause of this is still largely unknown. Early theories suggested that the progression was linked with increased immune responses — an idea that has since given way to a more plausible theory that the progression of the disease may be a result of nerve damage or loss. Researchers believe that bringing to light a better understanding of the progression of MS will ultimately lead to improved treatments in the future.
Source: BioNews
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