8.06.14
By Bill Hathaway – The autoimmune response
that is involved in multiple sclerosis (MS) was once thought to be confined to
the brain.
that is involved in multiple sclerosis (MS) was once thought to be confined to
the brain.
Yale researchers, however, have uncovered
evidence that this damaging response may begin in the lymph nodes.
evidence that this damaging response may begin in the lymph nodes.
The finding, reported in the issue of journal
Science Translational Medicine, tracks the origin of the autoimmune response in
the lymph nodes and later its arrival in the brain, where it contributes to
tissue damage that results in numbness, loss of vision, and debilitating
fatigue.
Science Translational Medicine, tracks the origin of the autoimmune response in
the lymph nodes and later its arrival in the brain, where it contributes to
tissue damage that results in numbness, loss of vision, and debilitating
fatigue.
“This helps explain why treatments that work
outside the central nervous system can ease MS symptoms and may give us clues
how to develop even more effective treatments,” said neuroimmunologist Kevin
O’Connor, one of the senior authors of the paper.
outside the central nervous system can ease MS symptoms and may give us clues
how to develop even more effective treatments,” said neuroimmunologist Kevin
O’Connor, one of the senior authors of the paper.
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