Real-world data sets show components of value-based care, use of Octave’s Multiple Sclerosis Disease Activity test and deep scan biomarker screening capabilities to evaluate evidence of disability, disease activity, and disease progression
Study presented in partnership with the Michigan Institute for Neurological Disorders highlights the promise of the Multiple Sclerosis Disease Activity test for patients in routine clinical use
February 25, 2023 08:00 AM Eastern Standard Time
MENLO PARK, Calif.–(BUSINESS WIRE)–Octave, a leading digital health sciences company that delivers a new standard for managing multiple sclerosis (MS) and other neurodegenerative diseases, today announced the presentation of nine abstracts at the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Conference 2023. The abstracts, presented in partnership with several of Octave’s premier research partners, included data on the company’s MRI Insights program as well as applications of the company’s clinically-validated Multiple Sclerosis Disease Activity (MSDA) test, including real-world data as well as new deep scan proteomic approaches. Research collectively underscored the strength and utility of the company’s Precision Care Solution for MS, which commercially launched in October 2022 and delivers quantitative, objective insights to better characterize individual patients’ underlying biology, response to therapeutic interventions, radiographic status, and evolving symptoms.
“We are thrilled to follow a very successful ECTRIMS meeting with an expanded body of research at this year’s ACTRIMS conference,” said William Hagstrom, Founder and Chief Executive Officer of Octave. “We’re adding to findings that have repeatedly shown the validity, quality, and adaptability of our solution, and now, we’re beginning to show real world applications as our clinical and research partners integrate these capabilities into their practices. The proof points we are building together have the potential to create a new standard of care for patients, and we’re grateful to our collaborators as they help us advance our mission to deliver holistic, comprehensive, biological, and contextual metrics that bring scientific clarity to MS.”
BIOMARKER POSTERS
First, Octave presented insights on the company’s first of its kind, MS-specific multivariate biomarker assay panel and leveraging deep scan proteomics in multiple posters at ACTRIMS Forum 2023. Highlights include a poster titled Proteomic Biomarker Panel for Gauging Multiple Sclerosis Disease Activity: A Case Series from Real-World Use (P035), Gonyou, T., et al., presented in partnership with the Michigan Institute for Neurological Disorders (MIND), describing real-world clinical experience using Octave’s MSDA test. The presentation reported on how the results from five diverse patient case studies reconciled with clinical presentation, radiographic evidence, and patient history, and how these additional insights into the underlying biology of MS support clinical decisions.
“We are excited to share results demonstrating that disease activity scores from the MSDA test appear to correlate with relapses and efficacy of therapy in a real-world setting,” said Taylor Gonyou, DO, Multiple Sclerosis Fellow at MIND and first author on the poster. “This test can be used to verify stability and may support the clinical decision to alter therapy. The ability to follow patients longitudinally will provide additional insights into patients’ disease activity, and allow treating neurologists to be confident in clinical decisions.”
Additional posters related to Octave’s multivariate biomarker assay panel include:
IMAGING POSTERS