Novartis Says MS Drug Gilenya Shows Long-term Efficacy, Safety In Extended Study

Stuart SchlossmanMS Drug Therapies, Multiple Sclerosis



6/11/2012 2:14 AM ET
(RTTNews) – Swiss drugmaker Novartis AG (NVS: News ) on Monday said a new data for multiple sclerosis drug Gilenya (fingolimod) showed long-term efficacy benefit and a consistent safety profile.
Gilenya, licensed from Japan’s Mitsubishi Tanabe Pharma Corp., is the only oral therapy approved to treat people with relapsing forms of multiple sclerosis.
The data from single-arm extension of phase III head-to-head TRANSFORMS study showed sustained reduction in relapses and rate of brain volume loss in patients on continuous Gilenya treatment for up to 4.5 years, the company noted
The results also showed improved efficacy for patients switched to Gilenya from Avonex (interferon-beta-1a IM), a commonly prescribed MS treatment from Biogen Idec Inc. Novartis noted that reductions in relapses and MRI measures were observed in these patients.

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