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Clinical results presented at the recent Academy of Managed Care Pharmacy (AMCP)‘s 2016 annual meeting in San Francisco showed that the use of H.P. Acthar Gel during multiple sclerosis (MS) relapses is associated with beneficial outcomes. The gel, according to its producer, is also available at a lower price than other frequently used drugs.
H.P. Acthar Gel, manufactured by Mallinckrodt Pharmaceuticals, has been used since the late 1970s for acute exacerbations of MS symptoms. The gel, which is injected to enable extended release of the drug, contains a highly purified preparation of adrenocorticotropic hormone (ACTH). ACTH triggers the body’s own corticosteroids — cortisol, corticosterone, and aldosterone — and might also affect B- and T-cells.
The drug is often prescribed for patients experiencing severe side effects of high-dose corticosteroids, or who have not responded well to corticosteroid treatment.
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