When you experience a multiple sclerosis relapse (also known as an exacerbation or flare-up), it’s because new damage in your brain or spinal cord disrupts nerve signals. That’s why you might notice new symptoms or the return of old symptoms. A true relapse lasts more than 24 hours and happens at least 30 days after any previous relapses. Relapses vary in length, severity, and symptoms. Over time, your symptoms should improve. Many people recover from their relapses without treatment.
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