Washington: Scientists claim to have found evidence that multiple sclerosis affects an area of the brain that controls cognitive, sensory and motor functioning apart from disabling damage caused by the disease`s visible lesions.
A team at the University of Texas selected the thalamus of the brain as the benchmark for its research published in the latest edition of `The Journal of Neuroscience`.
“The thalamus is a central area that relates to the rest of the brain and acts as the `post office`. It also is an area that has the least amount of damage from lesions in the
brain but we see volume loss, so it appears other brain damage related to the disease is also occurring,” Khader Hasan, who led the team, said.
Researchers have known that the thalamus loses volume in size with typical aging, which accelerates after age 70. The team`s purpose was to assess if there was more volume loss in patients with multiple sclerosis, which could explain the dementia-related decline associated with the disease.
“Multiple sclerosis patients have cognitive deficits and the thalamus plays an important role in cognitive function. The lesions we can see but there is sub-clinical activity in multiple sclerosis where you can`t see the changes.
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