Mouse DNA Stops Progression Of Multiple Sclerosis

Stuart SchlossmanMS Drug Therapies, Multiple Sclerosis, Tysabri

By Dayle Cedars, 7NEWS Reporter


Patients Get Infusion Of Tysabri Every Four Weeks

AURORA, Colo. — A tiny creature could hold the key to stopping the progression of multiple sclerosis. DNA from a mouse is being infused into patients. It’s FDA approved and patients are seeing results.

“I am not expecting a cure,” said Violet Lotito, who suffers from MS. “I am just expecting some help.”

Lotito loves being in the middle of the mix — either substitute teaching or cutting and styling hair.

But recently she couldn’t even stand, let alone work. Her MS got so bad, life wasn’t fun.

“The benefit hasn’t gone higher than the risk until now,” said Lotito. “Now that my symptoms have increased it is time to do something.”

Lotito turned to infusions of a drug called tysabri — a monoclonal antibody that contains DNA from a mouse and a human.

“Monoclonal antibodies are designed in the lab and they are specifically targeted toward specific molecules on white blood cells,” said Dr. John Corboy, of University of Colorado Hospital.





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