Long-term disability progression in primary progressive multiple sclerosis: a 15-year study.

Stuart SchlossmanMS Research Study and Reports, SPMS-PPMS News

Rocca MA, et al. Brain. 2017.

Abstract

Prognostic markers of primary progressive multiple sclerosis evolution are needed. We investigated the added value of magnetic resonance imaging measures of brain and cervical cord damage in predicting long-term clinical worsening of primary progressive multiple sclerosis compared to simple clinical assessment. In 54 patients, conventional and diffusion tensor brain scans and cervical cord T1-weighted scans were acquired at baseline and after 15 months.

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