Itchiness as a Symptom of Multiple Sclerosis

Stuart SchlossmanAdditional MS resource sites, Multiple Sclerosis (MS) Symptoms

By Julie Stachowiak, PhD  – Updated on May 12, 2024

Medically reviewed by Nicholas R. Metrus, MD

 Itchiness is just one of many symptoms of multiple sclerosis (MS). However, the underlying cause is different from other cases of itchiness, which are related to skin inflammation.

Multiple sclerosis causes itchiness due to the loss of the protective covering around nerves. Medications used to treat MS can also cause itchiness.

In this article, learn more about how MS causes itchiness and treatments.

Symptoms

Itching may be one of the first signs of MS. It can appear with other abnormal sensations caused by nerve problems such as pins and needles and burning or stabbing pains.1

MS-related itchiness is typically paroxysmal, meaning it starts and stops abruptly. This characteristic offers an important clue that MS is the likely culprit, unlike the many other possible causes of itchiness.

Itchiness in the same location on both sides of the body is another tip-off that this symptom is likely MS-related. Neuropathic itchiness related to MS usually occurs in specific areas of your body instead of feeling itchy all over.

Itchy sensations can occur virtually anywhere on your body, usually involving both sides. For example, arms, legs, or sides of your face might be involved. The itchiness may occasionally be confined to a single location, usually an arm or leg. 

While bouts of feeling itchy can happen six times per day or more, they usually only last a few seconds to minutes. These episodes can be very intense and disruptive, especially if they occur at night.

Some people experience a combination of abnormal sensations, such as itchiness and a burning or tingling feeling. Additionally, you might notice that specific circumstances trigger your bouts of itchiness.

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