Key takeaways:
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Acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) are both over-the-counter (OTC) medications for pain.
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Acetaminophen and ibuprofen work differently in the body. They are also cleared from the body by different organs. This makes it safe to use them together for additional pain relief if one alone doesn’t do the trick.
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You should never take more than the recommended daily amount of OTC pain medication. If your pain isn’t relieved, talk to your healthcare provider for other options.
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