High Intensity Training May Reverse the Fiber Type Specific Decline in Myogenic Stem Cells in MSers

Stuart SchlossmanMS Research Study and Reports


                                                                  

  


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Abstract

Multiple sclerosis (MS) is associated with loss of skeletal muscle mass and function. The myogenic stem cells (satellite cells-SCs) are instrumental to accretion of myonuclei, but remain to be investigated in MS. The present study aimed to compare the SC and myonuclei content between MS patients (n = 23) and age matched healthy controls (HC, n = 18). Furthermore, the effects of 12 weeks of high intensity training on SC and myonuclei content were explored in MS. 









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