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Yissum Research Development Company, an arm of Hebrew University of Jerusalem, has entered into an agreement with Aurum Ventures MKI to develop a diagnostic blood test for relapsing-remitting multiple sclerosis (RRMS) and a range of other diseases, which uses differences in DNA from dying cells found in the blood of sick individuals. DNA molecules are methylated to control the expression of specific genes, and specific methylation patterns exist in various tissues.
Researchers at the Hebrew University recently discovered that when cells start dying, the DNA is released and circulates in the bloodstream. By scanning hundreds of patients with various diseases, as well as healthy control individuals, they were able to identify methylation patterns that are specific for a number of conditions, including RRMS.
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