A worsening of the Expanded Disability Status Scale lasting at least six months is effective in identifying disease progression in patients with relapsing-remitting multiple sclerosis, according to a study published in the November issue of the Archives of Neurology.
THURSDAY, Nov. 11 (HealthDay News) — A worsening of the Expanded Disability Status Scale (EDSS) lasting at least six months is effective in identifying disease progression in patients with relapsing-remitting multiple sclerosis (RRMS), according to a study published in the November issue of the Archives of Neurology.
In a retrospective analysis of the Multiple Sclerosis Collaborative Research Group study data, Richard A. Rudick, M.D., of the Cleveland Clinic, and colleagues evaluated patients with RRMS who received at least two years of treatment and completed an EDSS evaluation eight years post-randomization.
The investigators found that 45 patients had sustained six-month EDSS progression, while 115 patients did not. Eight years after randomization, progression was the strongest predictor of reaching EDSS milestones at the follow-up visit. The investigators also found that treatment arm assignment and baseline EDSS score were other independent predictors of reaching EDSS milestones at the follow-up visit. Click here to continue
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