For many people with multiple sclerosis (MS), chronic pain is an ever-present companion that hampers their quality of life. Treating and managing chronic pain in people with MS is complicated, however. The pain they grapple with may be neuropathic pain, which is the direct result of damage to nerves in the central nervous system. Or it may be another kind of pain, like lower back pain or musculoskeletal pain that develops as a result of adjustments their bodies make to having MS. Many people with MS experience both kinds of pain. If you have MS, you may need to find a combination of various strategies to help you manage your pain—so you can regain more control over your life.