Information provided By Sharon Salem
2010 Expert-Reviews, LTD.
“Experimental allergic encephalomyelitis is … a true autoimmune disorder. It has been accepted as an animal model of multiple sclerosis … However, a false orthodoxy claiming that multiple sclerosis is an autoimmune disorder has developed and formed the present basis of treatment, drug trials and research. The outcome of this misplaced creed has been truly catastrophic.”
Multiple sclerosis (MS) is a chronic disease of unknown etiology that primarily affects the human CNS. While its pathology has been well described, its pathogenesis is still unknown. Multiple epidemiological studies carried out in Europe, the USA and Canada have highlighted the difficulty in its study because of the many complex combinatory roles of genetic factors, diagnostic variability and its often long symptomatic clinical course. In addition, there is no specific diagnostic test. All this may explain the great variability in the methodology of the multiple therapeutic trials for this disorder [1,2].
MS, acute disseminated encephalomyelitis & experimental allergic encephalomyelitis
The enigma of this curious disease can be demonstrated by the occurrence of MS being greater in first-, second- and third degree relatives, while its definite polygenic etiology still defies elucidation. The disease bears some clinical resemblance to acute disseminated encephalomyelitis (ADEM), a disorder that may occur spontaneously,
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