IRVINE, Calif., Aug 24, 2011 (BUSINESS WIRE) — Allergan, Inc. today announced the United States Food and Drug Administration (FDA) has approved BOTOX(R) (onabotulinumtoxinA) for injection for the treatment of urinary incontinence due to detrusor overactivity associated with a neurologic condition (e.g. spinal cord injury (SCI), multiple sclerosis (MS)) in adults who have an inadequate response to or are intolerant of an anticholinergic medication.(1) Urinary incontinence (bladder leakage) due to detrusor (bladder muscle) overactivity in patients living with MS or SCI is a chronic condition affecting approximately 340,000 people in the United States.(2) Current standard of care includes oral medications that are taken regularly, known as anticholinergics; however, it is estimated that 71 percent of people stop taking at least one oral medication within 12 months.(3) If oral medications fail, then surgery may be considered (e.g. implanting a neuromodulation device or bladder augmentation surgery).
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