Researchers reveal the hidden proteins that could hold the key to dementia and MS - Multiple Sclerosis (MS) Information, and resources

Amazing images show the proteins responsible for devastating brain diseases
Scientists plan to study them in the hope of finding new therapies

PUBLISHED: 06:39 EST, 26 September 2012

Scientists are to launch a major study of little-known proteins they believe are a contributing factor to diseases such as dementia and multiple sclerosis.

The team of biologists at the University of Portsmouth have been awarded £600,000 to research the impact on the ageing of the brain and cognitive decline.

The study will focus on a protein known as Kir4.1 which is a key element in controlling special cells in the brain and spinal cord which form myelin, a substance which insulates the brain’s wiring.

A close up image of oligodendrocytes, a protein scientists believe is a contributing factor to diseases such as dementia and multiple sclerosis.

They discovered that the protein is critical in ensuring these cells, known as oligodendrocytes, function well.

The researchers already know that myelin acts as the insulating layer around nerve cells and is essential for rapid conduction of information and when it is damaged this interferes with messages between the brain and other parts of the body.

They are also researching another protein called Gas6 which they have discovered can stimulate oligodendrocyte production and survival.

The team’s combined research will focus on signals in the brain which stimulate the growth and regeneration of oligodendrocytes and myelin.

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