Study reports that cells isolated from periodontal ligament stopped disease progression in mice
A new source of stem cells, the mesenchymal stem cells (MSCs) isolated from the human periodontal ligament (hPDLSCs), offers a potential treatment capable of halting multiple sclerosis (MS) progression. The study, “Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis,” was published in the Stem Cell Research & Therapy journal.
Current treatments for MS are administered only as a palliative relief, without a cure, and many are associated with adverse side effects. The development of techniques that allow for harvesting and culture of MSCs, especially those derived from the bone marrow, aids investigations into its properties in promoting tissue repair and disease control in the established mouse model for human MS, the experimental autoimmune encephalomyelitis (EAE) model.
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