November 1, 2016 /
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Changes in the composition of certain immune system cells may be associated with relapses in multiple sclerosis (MS) patients being treated with Gilenya (fingolimod), according to a study published in the journal Scientific Reports.
The study, “Altered T Cell Phenotypes Associated With Clinical Relapse Of Multiple Sclerosis Patients Receiving Fingolimod Therapy,” was conducted by researchers in Japan.
In MS patients, immune cells called T-cells penetrate the brain and react against the myelin coating that protects and supports neurons. But before this autoimmune response occurs, T-cells undergo certain migratory steps.
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