Lower Oxygen in Brain’s Gray Matter Linked to More Impairment in Mouse Study

                                                                  

The less oxygen that a mouse with multiple sclerosis (MS) has in the gray matter of its brain, the more mental and physical deterioration it is likely to have, a new study suggests.

The study confirms previous research indicating a connection between low oxygen levels in a mouse’s gray matter and the development of MS. Published in the journal Plos One, the study is titled, “Gray Matter Hypoxia in the Brain of the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis.”

These findings also offer additional evidence that MS can affect not only white matter, where the brain’s myelin-covered nerve fibers are located, but also gray matter. Many scientists once thought that MS affected only white matter.

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