Epileptic Seizures in Multiple Sclerosis May Suggest Shared Pathology

                                                                  

Patients with multiple sclerosis (MS) who experience seizures are more likely to be younger at the age of MS onset than patients with MS who do not have seizures, according to a study reported in Neurological Sciences by the Epilepsy Study Group of the Italian Neurological Society. The disease course also tended to be slightly more severe in patients with seizures.1

An overlap between MS and epileptic seizures has been observed in previous studies, although the significance of this is not well understood.2-7The most common condition to show a higher incidence and prevalence in MS is epilepsy, estimated in 1 meta-analysis at 2.28% and 3.09%, respectively, compared with a frequency of <1% in the general population.8,9

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