Secondary Progressive Multiple Sclerosis EBV Adoptive Immunotherapy Shows Promise

Stuart SchlossmanSPMS-PPMS News

secondary progressive multiple sclerosis and Epstein-Barr virusPosted by: Maureen Newman   February 10, 2014




Professor Michael Pender, of the University of Queensland School of Medicine, Brisbane, had a notion that patients with advanced multiple sclerosis, otherwise known as secondary progressive multiple sclerosis, have an impaired immunity to the Epstein-Barr virus(EBV).


 EBV is one of the most common viruses in humans, affecting 9 out of 10 people at some point in their lives, and is a member of the herpes family. Several studies have linked EBV to triggering patients’ MS, as increased levels of EBV antibodies have been found in MS patients’ blood and EBV-infected immune cells have been found in postmortem brains from MS patients. Although no causal relationship has been established, EBV exposure seems to increase an individual’s risk of developing MS.


Source: BioNews

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